What To Do When ED Medicines Fail?

Thanks to a lot of inter-consumer advertising, most men of a particular age know to ask about the “little blue pill” or similar drugs if they grow erectile dysfunction (ED). These drugs enhance blood flow to the spongy tissues within the penis, which creates an erection. Some of the most popular drugs for treating erectile dysfunction are sildenafil citrate 100mg, sildenafil citrate tablets 100mg, sildenafil citrate 20 mg, Cenforce 100, Cenforce 200, Vidalista 20 mg, tadalafil 20mg, fildena 100, fildena 150, fildena 100 mg, i 10 pill, fildena ct 100, etc.

However, the drugs don’t work for about 30% of men. Then what should be done?

Here are the alternatives to oral erectile dysfunction drugs. Solutions are available for most men’s needs.

Injections: subsequent best choice to oral medication is injecting a drug called alprostadil (Caverject, Edex) directly into the body of the penis.
The relatively shallow injection creates an erection within five to twenty minutes that lasts for up to an hour. Some men aren’t wild about sticking themselves with a needle, but it works. Possible risks include pain at the injection site or an unusually prolonged erection requiring medical attention.

Urethral pellet: Another option is the medicated urethral system for erection (MUSE). In this treatment, a pellet of alprostadil is inserted into the opening at the tip of the penis (the urethra), where it is absorbed through the urethra wall. It creates an erection within 10 minutes that lasts up to an hour. MUSE doesn’t work as well as injections and may cause irritation and pain.

Vacuum restriction: In vacuum restriction, the man places a plastic cylinder covering the penis and uses a pump to generate vacuum pressure in the tube, which lures blood into the penis. The erection is maintained for up to a half-hour by a snug rubber ring placed at the base of the penis. This is an alternative choice, but it doesn’t produce a true natural quite erection.

Penile implant: A more invasive option is a penile implant. Small hollow tubes are inserted in the penis. They can be inflated using a small pump implanted in the scrotum to make the penis erect, then deflated when no longer needed. The downside is that the implant disturbs the natural erectile anatomy, so oral drugs or injections will not work after an implant.

What is the ‘success rate’ of sildenafil (Viagra)?

From clinical trials the resulting percentages of men responded to the three different doses of sildenafil as follows:

  • 62% men who took Sildenafil  25mg dose reported improved erections
  • 74% men who took Sildenafil 50mg dose reported improved erections
  • 82% men who took Sildenafil 100mg dose reported improved erections.

The results show sildenafil (Viagra, Viagra Connect) isn’t effective for all men, but the explanations are often complex and varied. Read on to learn a few different things you can try in order to help your medication have the desired effect. These points will assist you to develop a sensible expectation for your treatment.

Adopt the right mindset

Before all else, you should try to convince yourself that no erectile dysfunction medicine may be a miracle cure and miracles anyway don’t happen overnight. The PDE5 inhibitors (sildenafil, tadalafil, vardenafil, and avanafil) work by facilitating blood flow to the penis, but all of them require arousal. Your body sends the required chemical to the blood vessels of the penis and therefore the medication helps you to urge an erection.

Sometimes medicines can't work to cure erectile dysfunction. What to do next?

Without proper arousal, the medication will simply not become. Try to confirm you’re receiving stimulation that works for you; whether it’s visual or from touch, scent or taste, you would like to feel naturally turned on.

Patient expectations

Psychological factors can make an enormous difference with reference to treatment and outcome, and will not be underestimated (the consequence may be a good example). Brand, size, shape, and colour of a pill can all have a psychological impact on a patient’s confidence within the treatment. There is also documented evidence that a better dosage can have a positive psychological effect, however side effects are more likely. Studies also suggest men’s mood improves after taking sildenafil.

Don’t eat before taking Viagra, Levitra, or Spedra

Many men make the blunder of taking Viagra, Levitra, or Spedra after a meal. This can hinder the absorption of the drugs, making them only marginally effective. You should wait a minimum of 2 hours after eating before taking the tablets so you’ll experience their full effect. Avoid eating fatty foods or drinking sour fruits, particularly grapefruit, as these may affect efficacy.

Cialis (tadalafil) is the exemption.

When you have Erectile Dysfunction, having sex may take more planning than before. For couples concerned about the loss of impulsiveness, low dose (2.5mg or 5mg) Cialis/tadalafil taken daily provides continuous treatment and requires less planning.

Also Read: The Ways For Medication Disposal

But if sex and intimacy is a night-time activity for you, it isn’t going to be much of an obstruction. Simply have a meal late in the day, take your medication a few hours later, and then just wait the required time before you plan to have sex. This leads us to our next fact:
Give yourself an hour

The medication takes a short time to enter your system and reach its peak effect, and therefore the time varies from Viagra to Spedra, Levitra, and Cialis. By waiting at least the required amount of time you will be giving yourself the best chance of achieving a full erection.
This also gives you and your partner time to get into the mood. Why not ease into the interlude by touching and kissing, lying down together, or maybe watching a sensual or erotic movie. As the pill takes effect you’ll begin to engage in foreplay leading up to sex, and this will make the experience less rushed and more enjoyable overall.

Keep trying

If your medication doesn’t work the first or the initial time, or maybe for the first few attempts, don’t lose confidence. It is suggested that you simply try the prescribed dosage a minimum of 8 times to measure its effectiveness. Your doctor can guide you on how long you ought to continue with this first dosage before considering any change to your medication.

Increased dosage or different Erectile Dysfunction medicine

The normal starting dose of Viagra (sildenafil) may be a 50mg tablet, but if this dosage isn’t effective it’s going to be increased to at least one 100mg tablet. Doses of other Erectile Dysfunction medications also can be increased. Increasing dosage also increases the potential for side effects.
Conditions like diabetes or cholesterol will affect whether you’re prescribed the upper dose, but if your Erectile Dysfunction medication isn’t working, a better dosage could be the correct course of action.
However, if your body still doesn’t respond to your treatment, it might be time to try a distinct medicine. Don’t think that merely because one tablet didn’t work then another can’t achieve success as well.

Many brands of sildenafil (generic Viagra) come as scored tablets, which implies that they can be broken into halves or quarters if needed to save a generous amount of money (eg: a 100mg tablet broken half provides 2 x 50mg doses). Drug manufacturers don’t recommend splitting tablets but it’s often common exercise by nurses. If you select to separate tablets break the tablet only at the time required, and store the remaining leftover part of the tablet inside a wrapped container or cling-film, to limit any dryness of the tablet. Generally, it is recommended to use the correct dosage tablet.
Many a time it gets exasperating trying to make out why you aren’t undergoing the stated results but there’s usually a reason, so consider the preceding factors and arm yourself with this information as you speak with your doctor.

Alprostadil to the Rescue

A drug called Alprostadil, either alone or sometimes in conjunction with others like papaverine and/or phentolamine, is very often injected directly into the penis to dilate the arteries, experts say. The drug generates an erection in about 10 minutes which will last up to an hour. But there are several disadvantages. Some patients are averse to employing a needle, which is why many men abandon the therapy. Some may endure pain at the injection site or priapism (a painful erection lasting too long).
As an alternate, Alprostadil is out there as a pellet-like suppository that’s inserted into the tip of the penis and absorbed through the liner of the urethra. This can help produce erections lasting for 30 to an hour. Unfortunately, the suppositories are less effective than injections and should cause pain and irritation.

A while back, a topical gel formulation of alprostadil was permitted by the U.S. Food and Drug Administration. It is to be seen if this type of alprostadil therapy will become widely used.

Mechanical Help

With a vacuum constriction device, the penis is placed under a cylinder with a linked pump, creating a vacuum to draw blood into the penis. Firmness is maintained by a constriction band placed around the base of the penis. The technique can produce erections for up to a half-hour. The side effects are minimal but it’s cumbersome and takes some preparation.

Some men choose penile implants, which involve the location of tubes within the penis and a pump within the scrotal sac. The pump (usually the dimensions and shape of a testicle) enables men to get an erection whenever and for as long as they desire by pumping saline from a reservoir into the penis.

If you’ve been using prescription drugs to fix your erectile dysfunction, take out some time to think about whether they are really working for you. If they aren’t, talk to your doctor about dosage or switch to another product. Even Cenforce 100, Cenforce 150 and Cenforce 200 work pretty well for treating erectile dysfunction. When you’ve exhausted your options, consider whether an alternate treatment like those discussed here could be your next most suitable option.





Tags: What is the latest treatment for erectile dysfunction, Which erectile dysfunction drug is best, Erectile dysfunction treatment options

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Janet Fudge

Janet Fudge writes on general health topics for CheapMedicineShop.com. She holds a post-graduate diploma in Public Health with a major in epidemiology. During the outbreak of COVID-19, Janet actively volunteered in vaccination drives throughout the state of Iowa. She lives in Iowa with her husband and two children.