Cenforce is a drug that manages the condition of erectile dysfunction exceptionally well. It is a drug that is manufactured by the Centurion Laboratories, which is counted as a reputed firm and they are the manufacturer and exporter of pharmaceutical drugs. Viagra is its equivalent US brand name and viagra is the branded drug that has same salt as cenforce and is available in the US market. It is one of the most recommended drugs to treat erectile dysfunction and this medicines is available in varying strengths. Erectile dysfunction is defined as a persistent inability to achieve and maintain satisfactory penile erection during sexual intercourse. Erectile dysfunction can be the result of psychogenic causes or organic causes. Psychogenic causes include the relevant pathways that are intact but psychological impairment is present. Organic causes include hormonal, neurovascular and anatomical risk factor. Both the factors can also result in the failure of erectile function.
Sildenafil is the active medical ingredient that is present in Cenforce and it belongs to the class of phosphodiesterase type 5 inhibitors. It plays a key role in treating erectile dysfunction and it is quite efficient in its working. An erection occurs when there is an increased blood flow in the penis. An erection begins with sensory and mental stimulation. Brain sends impulses to the local nerves in the penis when it senses a sexual urge and it leads to the relaxation in the muscles of the corpora cavernosa. It increases the blood flow and thereby helps in sustaining an erection.
Sildenafil enhances the effects of nitric oxide which plays an important role in smooth muscle relaxation. Sildenafil inhibits the phosphodiesterase type 5 enzyme and blocks the degradation of cGMP (cyclic guanosine monophosphate). An increased level of cGMP causes the smooth muscles to relax and increases the blood flow to the penis region. Hence an erection is maintained.
It should be noted that cenforce or sildenafil has no effect in the absence of sexual stimulation. The action of phosphodiesterase type 5 inhibitors depends on the nitric oxide and sexual stimulation is the stimulus of nitric oxide release. Without sexual stimulation or without nitric oxide release, this drug is of no use.
Safety Issues for Cenforce
1. Nitrates are contraindicated with Cenforce
It is essential to make sure that patients who are using any forms of nitrates such as nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate should not be taken with cenforce or with any phosphodiesterase type 5 inhibitor. It can result in decreased blood pressure and develops the symptoms of hypotension.
2. Antihypertensive drugs
It is known that antihypertensive drugs and PDE5 inhibitors interact with each other. Antihypertensive drugs such as angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, calcium blockers, and diuretics can lead to decreased blood pressure and increases the risk of complications.
3. Any other phosphodiesterase type 5 inhibitor
Do not take Cenforce if you are taking any other PDE5 inhibitor such as cialis or levitra. It can interact with Cenforce and can lead to major complications.
Important instructions to know before taking Cenforce
It is important to consult the doctor before taking Cenforce or any other drug and do not consume it without any consultation. The doctor will guide you about all the necessary thing about the drug and will also explain to you about how, when and for how long you should continue taking this drug. Also, as cenforce is available in varying strengths, take the strength as prescribed as a higher dose can be a complication. Generally, the starting dose is given according to the patient’s response and side effects, and the drug should be taken thirty to sixty minutes before the sexual activity. You can take it with a glass of water, with or without food but the efficacy of this drug reduced after the heavy and fatty meal due to prolonged absorption.
Also, after taking cenforce, a person might experience some side effects such as dizziness, headache and indigestion but generally the side effects of cenforce are mild. If you experience any severe side effect contact the doctor immediately to avoid any future complications. Do not take an overdose of this drug and read the label of the drug carefully and ensure that you are not allergic to any ingredient that is present in this drug. Always share your medical history and all the medicines you are taking with the doctor as he will guide you about any interactions.
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